5.3.2 Foldit

Foldit He nani hamama kahea, no ka mea, mau hiʻohiʻona nō nā kānaka'ē mākaukau e komo ai i ke ala i ka leʻaleʻa.

Ka Netflix uku, oiai evocative a me ka mōakāka, aole ia e kahaki i ka piha ana i ka laulā o ka hamama kahea papahana. No ka mea, laʻana, ma ka Netflix lua loa o ka poe i komo mea i na makahiki o ke aʻo i ka 'ikepili helu a me ka mīkini hoʻonaʻauao. Aka, e wehe ae kapa hana hiki no hoi pū i komo ka poe aole he olelo aʻo, e like me ka ua ia manaʻo ma ka Foldit, he kumuʻiʻo pelu hihiu.

Kumuʻiʻo pelu no ke kaʻina hana ma i ka lei o ka'amino nāʻakika lawe maluna o kona helehelena. Me kaʻikeʻoi aku ka maikaʻi o kēia kaʻina, biologists ke manao nā polokina me ka ho'ākāka kinona i hiki ke hoohana e like me ka laau lapaau. Simplifying kulana iki, nā polokina kamaʻilioʻana e neʻe aku i ko lakou haahaa ikehu AEI, he AEI e kaupaona i ka likeʻole pushes, a me pulls loko o ke kumuʻiʻo (Kii 5.7). No laila, ina he kanaka noiʻi manao e kilokilo i kinona i loko o ka mea i kumuʻiʻo e pa, i ka pāʻoihana kani puni; pololei hoao hiki a pau kŰia ke kau, e huli i ko lakou ikaika a, ae kilokilo ai ke kumuʻiʻo e pa iloko o ka haahaa ka ikehu hoʻonohonohoʻia. Eia naʻe, i kēia me nā mana kokoke kŰia i hoao hiki na kŰia ke kau mea computationally hiki ole, no ka mea, ua ieeeea? A ieeeea? Oʻia kŰia ke kau. A me na kamepiula 'ē aʻe kōkua i loaʻa: loa ikaika loa i keia la, a ma loko o ka wā e hiki mai foreseeable-me nā pūʻali koa, ua pono ole ana i ka hana. No laila, ua ulu nui akamai algorithms biologists e ka maiau huli i ka mea haahaa ka ikehu hoʻonohonohoʻia. Aka, hoʻowahāwahā papakaukau dala o iao? A computational ke kākoʻo 'ana, i keia mau algorithms ua malie loa mai ka hemolele.

Kii 5,7: kumuʻiʻo pelu. ua hana kii, a hoonoho iho la iloko o Aupuni ma "DrKjaergaard". Source: Wikimedia maoli .

David Baker, a me kona noiʻi pae ma ke Kulanui o Hawaii, he hapa o ke anaina kanaka o nā kānakaʻepekema hana e nā oi computational hoʻokokoke mai i ka kumuʻiʻo pelu. I mea e Track i ka hana ma o ko lakou mau algorithms i cranking aku, Baker, a me kona hui e occasionally, e makaala oukou i ka pale-saver i visualized i ka holomua o ko lakou mau algorithms. Oiai e kiai ana ia mau visualizations, hoomaka ae la Baker e haʻohaʻo nei ina paha he mea hiki i kānaka, e kokua mai ai i ke kaʻina, a pela i hoomaka ai Foldit, he makakū a me ka nani hamama kāhea (Hand 2010) .

Foldit huli i ke kaʻina hana o ka kumuʻiʻo pelu i loko o ka holoholona hihiu e hiki e hoʻokaniʻia e kekahi mea. Mai ke kuanaʻike o ka pâʻani pôpeku, Foldit mea akaka e lilo i Puzzle (Kii 5.8). ua hooku iho la ia Players i ka ekolu-dimensional hihipeʻa o ke kumuʻiʻo 'ole a hiki hana operations- "tweak", "wiggle", "kukulu hou" -that hoʻololi i kona helehelena. Ma ka lawelawe keia mau hana âlapa pôhili me hoʻololi i ke kinona o ke kumuʻiʻo, i ka huli emi paha o ko lakou Manual. Loi, ke manual he pōpilikia ma muli o ka ikehu-kiʻekiʻe o ka he hoʻonohonohoʻia; lalo-ikehu X ka hopena kiekieʻai. Ma kekahi olelo, ke manual kokua alakai i na âlapa pôhili e like me ko lakou imi no haʻahaʻa-ikehu kŰia ke kau. Keia holoholona hihiu, he wale nō e hiki, no ka-pono luaÿi Movie lākiō i loko o ka Netflix makana-kumuʻiʻo pelu e like me ka mea no hoi he kahua kahi e hiki e huli pāʻoihana ma mua o paha lakou.

Kii 5,8: Game paku no ka mea, Foldit.

Foldit ka leo hone manao mau hiʻohiʻona nō âlapa pôhili me uuku kūlana ike o ka biochemistry e paʻi me ka maikai algorithms papahana e akamai. Oiai ka hapanui o âlapa pôhili me heʻaʻole maopopo maikaʻi ma ka hana, aia no he poe ua loaʻa kekahi mau âlapa pôhili me a uuku hui o na âlapa pôhili. In mea, i loko o ka poo-i-poo Competition e kilokilo i ke 'ole o ka 10 ho'ākāka' ia nā polokina, ua hiki ke kuikui noho-o-ka-oe kumuʻiʻo pelu algorithms elima manawa Foldit Band (Cooper et al. 2010) .

Foldit, a me ka Netflix makana, heʻokoʻa ma na aoao, aka, laua a elua Komo hamama kelepona mai no ka pāʻoihana ka poe pono o ka nānā mamua paha. Ano, e ike kakou i ka like 'ole ma kekahi manawa okoa' okoʻa: iaoaioa kanawai. Keia hope loa mamuli o ka hamama kahea pilikia hōʻike ia lakou hiki ke hoʻohana 'no hoi i ka napoo ana no hoi i ka poe iʻae nō hoʻi amenable i ka quantification.